Two Postdoctoral Positions at Lund University

The fellows will become experts on the basic mechanisms of fuel-stimulated insulin secretion, the failure of which is ultimately the cause of Type 2 Diabetes (T2D). Secretion of the hormone is controlled by metabolism of fuels in the beta-cell. Cellular metabolism generates coupling signals, which impact on ion channels and/or the exocytotic machinery in the beta-cell. The current lesson from the genome-wide association studies (GWAS) of T2D is that most identified gene variants associated with the disease are implicated in in beta-cell function. Although these associations are firmly established, the mechanisms whereby they cause disease have remained unresolved. This hampers proper prevention of T2D and development of drugs for “Precision Medicine”.

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Two Postdoctoral Positions at Lund University