1-2 Postdoctoral Researchers in Mitochondrial Genetics at Karolinska Institutet

The research at the Division of Molecular Metabolism aims at understanding the regulation of mitochondrial function and the role of mitochondrial dysfunction in disease and ageing. Using patient material and different animal models, our overall aim is to get insights into disease pathophysiology and to develop novel treatments.

To study the regulation of mitochondrial function with special focus on gene expression, the role of mitochondrial DNA (mtDNA) mutations in disease and ageing, and fundamental principles for maternal transmission of mtDNA. Mitochondria are essential for cell function and mitochondrial dysfunction has been implicated in a variety of hereditary diseases, age-related diseases and the normal ageing process. Using mouse models, biochemistry, molecular biology and modern -omics approaches, the group of Nils-Göran Larsson focuses on understanding molecular processes determining how mitochondrial dysfunction causes disease and ageing.

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1-2 Postdoctoral Researchers in Mitochondrial Genetics at Karolinska Institutet