Up to four postdoctoral fellowships of 2 years each are available to study mechanisms that guarantee mitochondrial DNA stability in eukaryotes. The research will be carried out at the Department of Medical Biochemistry and Biophysics that offers a stimulating international research environment.
Mitochondria are organelles that produce cellular energy in the form of ATP. The mitochondrion is a unique organelle since it contains multiple copies of a double-stranded circular DNA genome, mtDNA, that encodes for core components of the energy-producing machinery. The mtDNA-encoded subunits are essential for efficient energy production, whereby it is crucial that mtDNA is maintained intact and at a sufficient copy number. Defects in mtDNA maintenance can lead to cellular energy deficiency and manifest as mitochondrial disease.
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Four Postdoctoral Fellowships at Umeå University