Postdoctoral Fellowships, Max Planck Institute for Biology of Ageing, Autophagy & Cellular Ageing, Germany (2018)

The focus of the research group “Autophagy and Cellular Ageing” is (1) to understand how cells regulate and perform autophagy at system-wide level and in mechanistic detail and (2) to gain comprehensive inside in the mechanisms and processes that underlie cellular ageing. We are mainly studying the yeast S. cerevisiae and apply a multidisciplinary approach combining genetics, genomics, systems biology, cell and molecular biology, high content imaging and flow cytometry. Using synthetic biology in two separate projects, we have developed two cell systems in yeast which allow us to monitor autophagy and mitotic/replicative ageing, respectively, on genome-wide scale at single-gene resolution in a fully automated manner. We are now aiming at determining the metabolic and genetic landscape of autophagy regulation and mitotic ageing. Downstream analyses will unravel the cell biological underpinnings of identified functional gene cluster. Discovered principles will also be tested for evolutionary conservation in higher organisms. We seek highly motivated, ambitious, and talented scientists to be part of an enthusiastic and collaborative team in an outstanding scientific environment.

This post is available from the earliest time point.

Qualifications
The successful applicant will hold a Ph.D. in a relevant research area such as biology, molecular biology, genetics or biochemistry and have a strong track record of accomplishment. The applicant should have a keen interest in the biology of autophagy and ageing, and excellent written and oral communication skills. Experience with cell biology, biochemistry or high throughput screening methods is essential. Familiarity with bioinformatics and fluorescence microscopy is a plus. The working language is English; knowledge of the German language is not required.

Further details:
Postdoctoral Fellowships, Max Planck Institute for Biology of Ageing, Autophagy & Cellular Ageing, Germany (2018)