PhD student positions at Friedrich-Alexander-University of Erlangen-NürnbergDepartment of Biochemistry | Γερμανία

Background

The lab is interested in signal transduction pathways regulating different aspects of myogenesis and formation/maintenance of neuromuscular synapses.

Projects

The projects in the lab deal with better understanding of molecular pathways in myogenesis in health and disease. To this end, we use genetically modified mice with floxed alleles. We analyze muscle phenotypes of mutant mice by their behavior, grip strength measurements, and histological / histochemical / immunostainings of muscle sections. We investigate the NMJs of the mutant mice by structural and functional approaches, like 3D morphometrical imaging, and electrophysiological recordings of neuromuscular transmission. Muscular target genes will be analyzed by RNA-Seq. Altogether, our projects help to understand individual and concerted roles of both intracellular signaling pathways regarding neuromuscular biology.

Desired skills and experience

You should be a young motivated scientist with excellent marks and willing to use this opportunity for your scientific career. Our lab is speaking english and german language (you should be able to speak at least english). PhD student candidates should have a degree in a relevant field.

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