Research Fellow positions are open in the Division of Endocrinology in the laboratories of Drs. Sanchez-Gurmaches and Nakamura.
The goal of Dr. Sanchez-Gurmaches lab is to understand the mechanisms that drive the normal and pathological formation and function of distinct types of adipocytes with the long-term goal of finding new therapeutic approaches to prevent or treat obesity and type 2 diabetes. For this we are using a wide variety of mouse genetic models to study adipocyte stem cells in different fat depots, induced pluripotent stem cells (iPSC) models, human clinical fat samples, single cell-omic tools, CRISPR screenings, omics approaches and functional in vivo and in vitro studies among others, following our recent findings (Cell Metabolism 2012, Nature Comm 2014, Stem Cell Reports 2015, Cell Metabolism 2018, Molecular Metabolism 2019).
The Nakamura lab studies the role of extracellular vesicles (EVs) in the regulation of systemic metabolism and in the pathogenesis of obesity. We aim to develop projects investigating tissue-specific EVs and small RNAs in the EVs in the pathogenesis of obesity-associated diseases, mainly type 2 diabetes and non-alcoholic fatty liver disease, based on our recent findings (Cell 2010, Nature 2012, Diabetes 2014, PNAS 2015, Cell Reports 2015, bioRxiv 2018, Nature Comm 2018). The successful candidates will engage in molecular/cellular/genetic studies with our newly established mouse models, iPSC models, and human clinical samples to critically understand the roles of EVs in obesity and obesity-associated metabolic disorders and comorbidity.
Requirements:
We are seeking applicants, with a recent Ph.D. or equivalent, who have peer review publications, high capacity for independent thinking, collaborative work, and problem solving and show motivation and implication for the area of research. Candidates with strong experience in mouse study as in vivo model, cell culture techniques, molecular biology, biochemistry, metabolism, immunology and/or, microscopy are encouraged to apply.
For more information please visit the following link:
Postdoctoral Positions, Cincinnati Children’s Hospital Medical Center, U.S.A.