Science for Life Laboratory (SciLifeLab) is a collaboration between four universities in Stockholm and Uppsala: Stockholm University, the Karolinska Institute, the Royal Institute of Technology, and Uppsala University. The SciLifeLab is a national center for large-scale biosciences with a focus on high-throughput health and environmental research. The center combines advanced technical know-how and cutting-edge equipment with a broad knowledge in translational medicine and molecular biosciences. In particular, SciLifeLab has in the recent years become an international hub for research in single-cell and spatial transcriptomics.
Stockholm University is a leading European university offering a multicultural environment in one of the world’s most dynamic capital cities. With more than 60,000 students and 5,000 staff, the University facilitates individual and societal development by providing top quality education that is tightly linked to its internationally recognized research programs. The MBW department conducts experimental basic research in molecular cell biology, integrative biology and infection and immune biology.
Research project
The postdoctoral positions are available in the Quantitative RNA Biology group headed by associate professor Marc Friedlander, part of MBW and located at the SciLifeLab. The group is part of a larger vibrant international collaborative environment and seeks to address fundamental questions in RNA biology, by applying quantitative approaches such as single-cell RNA sequencing, single-cell proteomics, various high-throughput screening methods and advanced computational biology.
Recent collaborations include paleotranscriptomic profiling of mammoth non-coding RNAs and study of the impact of space flight on the human transcriptome (NASA Twin study). The main focus of the group is to study microRNA functions in mammalian single cells, investigating the impact of microRNAs on target gene expression variation, covariation and on overall gene expression networks.
Further details:
Two postdoctoral researchers to study microRNA functions in single cells at Stockholm University