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University of Utrecht is looking for highly self-motivated Msc students with a degree in Medicine or Biomedical Sciences who are looking for an ambitious PhD project. The PhD students will be involved in relatively small-scale human intervention trials, in which she/he will perform a thorough characterization of 24h muscle metabolism and insulin sensitivity after timed food intake and timed exercise (training). For this, we will make use of techniques such as indirect calorimetry, hyperinsulinemic-euglycemic clamps and magnetic resonance spectroscopy.