The broad theme of this research project is the Development of strategies to prevent and treat fatty liver disease. The PhD student will perform lab-based studies in mice (phenotypic characterization) that are treated with different compounds and diets. In particular, liver samples will be studied in more detail in respect to expression patterns, epigenetic alterations (DNA methylation) and lipid profiles. Our overall objective is to enhance our knowledge on physiological changes that occur during obesity, insulin resistance and diabetes and to translate this to humans.