The automotive sector faces disruptive transformation within the next years. "Smart Systems for Clean, Safe and Shared Road Vehicles" will be at the heart of the answer to these disrupting changes. Thus, this will be the topic of this year’s 22nd edition of the International Forum on Advanced Microsystems for Automotive Applications (AMAA) to be held on 11-12 September 2018 in the Kaiserin Friedrich House, Berlin, Germany (www.amaa.de).