Fifteen (15) PhD Postions in Alzheimer's Disease, Marie Sklodowska Curie Actions SyDAD, Europe (2016)

SyDAD is an interdisciplinary PhD programme including an innovative research programme with cutting edge methodology, an excellent training programme, international exchanges and a translational and collaborative orientation.

Aims:
- To foster a new generation of researchers with an innovative mind-set and full understanding of the requirements of academia, pharmaceutical companies, the clinics and the societal challenges.
- To, through a collaborative research programme, elucidate how the different pathways underlying synaptic dysfunction in Alzheimer Disease (AD) relate to each other, to identify novel pharmaceutical targets and to elaborate a drug discovery platform.

More information on SyDAD: www.sydad.eu

The doctoral education projects and the duties of the student
The doctoral students will use biochemical, cell biological, electrophysiological and in vivo methods as well as clinical material. The network has access to a wide repertoire of cutting-edge methodology including super-resolution microscopy, mass spectrometry, in vivo electrophysiology and optogenetics. The doctoral students will be seconded to other sites of the network during shorter periods to best utilize the resources of the network and participate in a common training programme at the different sites of the network.

Projects:
For more information about the projects, please see the SyDAD web site www.sydad.eu

The applicants are asked to send separate applications directly to each organisation and to provide a list of which SyDAD projects (maximum three) they have applied for.

Karolinska Institutet, Stockholm, Sweden:
ESR 10: Targeting Cholesterol homeostasis and synaptic maturation. Contact: angel.cedazo-minguez@ki.se
ESR 11: Synaptic proteome and Aβ interactome in AD brain and mouse models. Contact: susanne.frykman@ki.se
ESR 13: EEG as a functional central biomarker in AD. Contact: vesna.jelic@ki.se
ESR 14: Mitochondria stabilisers and synaptic function in AD. Contact: maria.ankarcrona@ki.se

Apply to the projects at Karolinska Institutet at http://ki.se/en/about/jobs-at-karolinska-institutet

University of Bordeaux, France:
ESR 2: Role of APP in presynaptic mechanisms. Contact: gael.barthet@u-bordeaux.fr
ESR 7: Mitochondrial dysfunction in relation to synaptic function in mouse models of Alzheimer’s disease. Contact: Sandrine Pouvreau sandrine.pouvreau@u-bordeaux.fr
ESR 12: Plasticity of local hippocampal circuits in mouse models of Alzheimer's disease: relation with episodic memory encoding. Contact: christophe.mulle@u-bordeaux.fr

Apply to the projects at University of Bordeaux by e-mail: christophe.mulle@u-bordeaux.fr

University of Milano, Italy:
ESR 1: Linking actin-dependent dendritic spine remodelling and ADAM10 activity in AD: the role of CAP2. Contact: monica.diluca@unimi.it
ESR 9: A spine to nucleus signalling pathway in Alzheimer's disease. Contact: fabrizio.gardoni@unimi.it
ESR 15: Development of cell permeable peptides capable of increasing ADAM10 activity. Contact: monica.diluca@unimi.it

Apply to the projects at University of Milano by e-mail: monica.diluca@unimi.it and fabrizio.gardoni@unimi.it

Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany
ESR 3: Cascade linking Aß and tau-dependent toxicity to synapse loss. Contact: Mandelkow@dzne.de
ESR 4: Loss-of-function genetic screening using CRISPR/Cas9. Contact: Daniele.Bano@dzne.de
ESR 8. Synaptic plasticity and calcium remodelling. Contact: office-nicotera@dzne.de

Apply to the projects at DZNE by e-mail: application@dzne.de

Janssen Pharmaceutica NV, Beerse, Belgium
ESR 6: The roles of physiological and pathophysiological tau in synapse function and morphology. Contact: jpitaalm@ITS.JNJ.com

Apply for the project at Janssen here: http://jobs.jnj.com/s/u3z0MT

Axon Neuroscience, Bratislava, Slovakia
ESR 5: Rescue of truncated Tau-mediated synaptic dysfunction in vivo. Contact: novak@axon-neuroscience.eu

Apply to the projects at Axon by e-mail novak@axon-neuroscience.eu
Desired skills and experience

Entry requirements
The entry requirements for each participating university will apply.

Entry requirements of Marie Sklodowska-Curie Actions:
The applicant should be a postgraduate researcher in the first four years (full-time equivalent) of their research activity, including the period of research training, who has not been awarded a doctoral degree.

Note! Mobility rule: The researcher must not have resided or carried out his/her main activity (work, studies, etc) in the country of his/her host organisation for more than 12 months in the 3 years immediately prior to his/her recruitment.

Skills and personal qualities
- The applicants should have a genuine interest and solid education in Neuroscience at a master level or equivalent.
- The applicants should have excellent practical skills in performing laboratory work. For specific requirements for the different projects, please contact the respective supervisor.
- The applicants should have substantial experience in performing independent research projects, e g a Master thesis project
- The applicants should have good collaborative skills and be open-minded.
- The applicants should show good proficiency in written and spoken English equivalent to TOEFL or IELTS.

Further details:
http://www.researchgate.net