XPOSE is a doctoral training program focused on exposome & health. It aims to deepen our understanding of the interplay between environmental exposures and biological responses and how this leads towards the development of diseases across all stages of life. The scientific program addresses three critical facets of the human exposome: (i) environmental factors, (ii) social and behavioral factors and (iii) biological processes. Xpose will combine conventional and innovative approaches to identify modifiable factors that modulate exposure and health consequences in order to develop innovative interventions in the future. The program is supported by the PRIDE block grant of the Luxembourg National Research Fund (FNR).