University of Padua is seeking two post-docs to join the group and push forward published and unpublished work on the role of mitochondria as transducers of mechanical signals in physiology and disease.
The laboratory of Prof. Sirio Dupont in the Department of Molecular Medicine of the University of Padova is interested in understanding how the mechanical tissue mitcoenvironment regulates key signaling processes and metabolic pathways, and the importance of such regulations towards the development of novel therapeutic approaches to combat metastasis relapse.
Prof. Dupont spearheaded the discovery that YAP/TAZ proteins respond to the mechanical properties of the extracellular matrix, and how this pathway regulates homeostasis and cancer development in the mouse liver (Dupont Nature 2011; Aragona Cell 2013; Pocaterra J.Hepatology 2019; Pocaterra Comms Bio 2021).