Two PhD Candidates in Characterization of Bionanoparticles for Vaccine Delivery and Gene Therapy

As a PhD candidate at LUMC, you will be responsible for developing analytical tools to characterize bionanoparticles (such as AAVs and VLPs) and their encapsidated genomic material. These tools will enable you to delve deeper into the structural features of bionanoparticles with the final goal of understanding the influence of process conditions on bionanoparticle composition and eventually product efficacy. Your main tasks include:

• Developing and appling cutting-edge analytical techniques including mass spectrometry (MS) and advanced separation techniques such as multidimensional liquid chromatography or capillary electrophoresis for in-depth examination of bionanoparticles.

• Analyzing extensive datasets to gain insights into the structure and function of bionanoparticles.

• Actively collaborating with an international network of academic and industrial partners within the CAARE project, working both at LUMC and partner locations.

Additionally, you will publish your research results in scientific journals and present at international conferences. You'll have the opportunity to mentor students during their internships and work in a multidisciplinary team of analytical and organic chemists, biologists, and clinicians within the LUMC Center for Proteomics and Metabolomics. You'll be supported by a strong network of experts and have ample opportunities for further professional development