Doctoral students in vascular biomechanics at KTH Royal Institute of Technology

Cardiovascular diseases account for more than 30% of deaths, which are often related to mechanical failure at the vascular tissue level. However, surprisingly little is known concerning the multi-scale biomechanical mechanisms that lead to the rupture of the affected biological tissue..

Within a consortium of engineers, scientists and clinicians we plan to explore (structure-mechanical) factors that determine tissue rupture and therefore classify the health-related risk of a diseased vessel segment. In vitro experimental characterization of pathological vascular tissue is combined with the development of computational models towards patient-specific risk assessment. Our efforts relate particularly to diseased carotids and aneurysmatic aortas.

All actions are implemented through a tight interaction of the solid and fluid biomechanics research groups at the Department of Engineering Mechanics at KTH Royal Institute of Technology and the Department of Vascular Surgery at Karolinska University Hospital and Institute. Our translational research effort builds upon long-lasting and well recognized research results as well as it complements synergistically with other activities in our groups, guaranteeing the efficiency of the action.