3 Postdoctoral Positions, New York University School of Medicine, U.S.A. (2018)

Three postdoctoral positions are available in the Department of Pathology at NYUSoM to study (1) Ion Channels in Immunity to Infection, Tumors & Autoimmunity (Feske lab) or (2) STAT Proteins in Hematopoietic Malignancies (Levy lab) and (3) Hematopoietic/Leukemia Stem Cell Biology (Park lab)

Details and Requirements:
(1) Ion Channels in Immunity to Infection, Tumors, and Autoimmunity: A postdoctoral position is available in the laboratory of Dr. Stefan Feske, which has long-standing expertise in investigating calcium signaling pathways in cells of the immune system. We study the molecular regulation of calcium release-activated channels (CRAC) formed by ORAI and STIM proteins and investigate their role in the physiology of immune cells. We use mice with targeted deletion of CRAC channels and human patients with mutations in CRAC channel genes to investigate how calcium signals control immune responses to infection and tumors, and in autoimmunity and inflammation. Besides CRAC, other ion channels also regulate T cell-mediated immunity to pathogens, tumors, and self. We seek applicants to study this area of research in the Feske Lab. Our research is published in leading journals including Nature, New England Journal of Medicine, Immunity, Nature Immunology, Nature Communications, J Exp Med, J Clin Invest and PNAS. The lab is part of a large and vibrant immunology and cancer research community at NYUSoM. For more information, please visit: http://labs.pathology.med.nyu.edu/feske-lab/.
We are seeking motivated and creative postdoctoral scientists with a recent MD, PhD or MD/PhD degree who are interested in pursuing projects in the area of ion channels in immunity. Candidates should have a strong background in T cell function that includes experience in analyzing T cell-mediated immune responses using mouse models. Candidates with experience in ion channel function in immune cells or other cell types are especially encouraged to apply. A background in molecular and cell biology is desired. Please send a cover letter explaining relevant work experience and interests, a CV, and the contact information of three references to Dr. Feske at feskes01@nyumc.org.

(2) STAT Proteins in Hematopoietic Malignancies: Current project is directed at understanding the interacting roles of STAT1 and STAT3 proteins as tumor suppressors and tumor promoters in hematopoietic malignancies with an emphasis on myeloproliferative and lymphoproliferative diseases. The project makes extensive use of genetically-modified mouse models, molecular genetic analyses, and biochemical approaches. We are seeking motivated and creative postdoctoral scientists who recently completed PhD or MD studies and are interested in the molecular basis of cell signaling. Successful candidates will have the opportunity to participate in the Molecular Oncology and Tumor Immunology Training Program, sponsored by the National Cancer Institute, and the full intellectual environment of the Perlmutter Cancer Center. Candidates with a background in molecular biology and hematopoiesis are preferred. US citizens and permanent residents are especially encouraged to apply. Please contact Dr. Levy with your CV at David.Levy@nyumc.org. For more information, please visit: https://med.nyu.edu/faculty/david-e-levy.

(3) Hematopoietic/Leukemic Stem Cell Biology: A postdoctoral position is available immediately in the laboratory of Dr. Christopher Park for a highly motivated candidate to join a fast-moving, team-oriented research group interested in identifying molecular mechanisms that regulate normal and disease stem cells in the hematopoietic system. Areas of interest include hematopoietic stem cell biology (especially during aging), acute leukemias, and the myelodysplastic syndromes. The candidate will identify genes that regulate stem cell function by evaluating normal and disease stem/progenitor cells using a myriad of cutting-edge “-omics” approaches. Evaluation of gene function will include extensive use of stem cell transplantation assays, both using mouse models of disease as well as xenotransplantation models. For more information, visit: http://nyulangone.org/doctors/1386786317/christopher-y-park or http://chrisparklab.com/

Applicants should hold a PhD and/or MD degree and have strong laboratory and analytical skills as well as a desire to work with stem cell transplantation models. Those with prior experience in hematopoietic/leukemia stem cell biology are especially encouraged to apply, but those with strong backgrounds in molecular biology/biochemistry, cancer biology, or computational approaches to evaluate high throughput data are also welcome to apply. Qualified candidates must have a recent Ph.D. and/or M.D. and must have a record of peer-reviewed publications and must have good written and oral communication skills. Full applications including curriculum vitae, a summary of current and future research interests, expected availability date, a description of past research experience and accomplishments, selected reprints of publications, and three references should be submitted to Dr. Park at Christopher.Park@nyumc.org.

Further details:
3 Postdoctoral Positions, New York University School of Medicine, U.S.A. (2018)