Project: Christophe Heinrich “Cellular Reprogramming and Brain Repair” was recently awarded a LabEx Attraction Package at SBRI. Our group focuses on direct lineage reprogramming of somatic cells into induced neurons as a novel cell-based therapy for brain repair. We previously showed that glial cells can be converted into functional induced neurons (Heinrich et al., PLoS Biology 2010, Nature Protoc 2011, Stem Cell Reports 2014, Nature Cell Biology 2015; Karow et al., Cell Stem Cell, 2012).