Bioactive components in milk, e.g. cell-derived extracellular vesicles (mEVs), are essential for a kick-start of life. However, the mechanism of action (MOA) of these components is poorly understood. As a PhD in this project, you will decipher the MOA of mEV-mediated metabolic modulation of immune, liver and neuronal cells, analyse mEV composition during lactation, and investigate the impact of milk processing on mEVs.
The positions are supported by the public-private Health Holland TKI-LSH SIGNALERS Project, aiming to unlock the MOA of human mEVs.