Three (3) Postdoctoral Positions in Normal & Malignant Hematopoiesis, University of Copenhagen, Denmark (2015-2016)

We are searching for highly motivated and talented postdocs to join our team working on mechanisms governing normal and malignant hematopoiesis. We will recruit up to three postdocs with either an experimental or a bioinformatics background.

Our research/the group
Research in the Porse group is focused on elucidating mechanisms governing normal and malignant hematopoiesis with special emphasis on the behaviour of hematopoietic stem cells (HSCs) during adult hematopoiesis and leukemic stem cells (LSCs) in acute myeloid leukemia. To this end, we employ mouse models of human AML, mouse knock-out lines of putative HSC/LSC regulators, primary patient material and a broad range of bioinformatics tools. We have also conducted a number of shRNA-based in vivo screens for genes involved in tumor maintenance and identified a number of novel potential oncogenes and tumor suppressors which will be studied in future projects.

Project/the research project(s)
A number of projects under the headlines listed below are available for the successful applicants.
- Characterisation of novel candidate oncogenes and tumor suppressors in AML
- Characterisation of putative HSC/LSC regulators
- In vitro approaches for the generation and/or maintenance of HSCs
- Bioinformatics analyses of genome-wide datasets (Chip-seq and/or gene expression experiments) in normal and malignant hematopoiesis

Further details:
http://www.researchgate.net