Twelve (12) PhD Positions, European Training Network Brain Barriers Training – BtRAIN, Europe & USA (2015-2016)

The European Training Network Brain Barriers Training – BtRAIN invites applications for 12 positions for Early Stage Researchers (ESR)/PhD students.
BtRAIN fosters contacts of 12 academic and 6 non-academic partners from 7 EU countries, CH, USA and the European Network Brains4Brain.
Research in BtRAIN (www.btrain-2020.eu) is dedicated to create and disseminate unique knowledge on the vertebrate brain barrier signature genes and their specific role in regulating brain barrier function in development, health, ageing and disease. BtRAIN will train a new generation of young researchers to think out of the box and to bridge disciplinary interfaces.

Description
BtRAIN provides a trans-disciplinary and trans-sectorial environment, combining the expertise of clinical and non-clinical researchers in biomedical disciplines (developmental biology, vascular and cell biology, physiology, pharmacology, neuroimmunology) and technologies (chemistry, bioenigneering and imaging of the brain barriers) with that of bioinformatics from the academic and non-academic sector.

The following BtRAIN projects are available
Project 1: In vitro models of the blood brain-barrier and applications in pharmacological and toxicological screenings
Project 2: In vitro models of the blood-brain and blood- cerebrospinal fluid barriers using an integrated microfluidic device
Project 3: Comparison of mouse and zebrafish cerebral endothelial cell transcriptomes and functional investigation of conserved pathways governing brain angiogenesis and BBB formation
Project 4: Integrative meta-analysis of public and novel vertebrate BBB omics data and establishment of the BBBhub platform
Project 5: Role of the orphan G-protein-coupled receptor Gpr126 signalling in the development of the blood-brain barrier
Project 6: Age-induced changes in gene and microRNA expression at the mouse blood-brain barrier
Project 7: Blood-brain barrier derived non-conding RNAs as functional biomarkers for the aging BBB versus the BBB in Alzheimer’s Disease
Project 8: Brain endothelial mechanisms directing the cellular pathway of T cell migration across the BBB
Project 9: Contribution of the BBB in amyloid-b biology in Alzheimer’s disease
Project 10: Exploring CD4+ T cells as carriers to mediate transport of drugs across the blood-brain barrier
Project 11: Role of different receptors in promoting pathogen and leukocyte migration across the brain cerebrospinal fluid barrier in meningitis
Project 12: Molecular control of the human brain barriers in health and neuroinflammation

Further details:
http://ec.europa.eu